Pfizer Handbook of Microbial Metabolites 



38 



Streptomyces griseus (Krainsky) Waksman et Henrici 

 S. bikiniensis, S. mashuensis 



Albert Schatz, Elizabeth Bugie and Selman A. Waksman, 

 Proc. Soc. Exptl. Biol. Med. 55 66 (1944). (Isolation) 



Selman A. Waksman, "Streptomycin, Its Nature and Appli- 

 cations," Williams and Wilkins Co., Baltimore, Md., 1949. (A 

 review ) 



Herbert E. Carter, R. K. Clark, Jr., S. R. Dickman, Y. H. 

 Loo, P. S. Skell and W. A. Strong, J. Biol. Chem. 160 337 

 (1945). 



Frederick A. Kuehl, Jr., Robert L. Peck, Charles E. Hoffhine, 

 Jr., Robert P. Graber and Karl Folkers, J. Am. Chem. Soc. 68 

 1460 (1946). 



Frederick A. Kuehl, Jr., Edwin H. Flynn, Norman G. Brink 

 and Karl Folkers, ibid. 68 2096, 2679 (1946). (Structure) 



I. R. Hooper, L. H. Klemm, W. J. Polglase and M. L. 

 Wolfrom, ibid. 69 1052 (1947). 



H. E. Carter, R. K. Clark, Jr., S. R. Dickman, Y. H. Loo, 

 P. S. Skell and W. A. Strong, Science 103 540 (1946). 



E. P. Abraham and H. W. Florey, "Antibiotics," Oxford Uni- 

 versity Press, London, 1949 Vol. II chap. 41, pp. 1297-1309. 



E. P. Abraham, ibid. chap. 42, pp. 1310-1326. 



55 Hydroxystreptomycin (Reticulin) C2iH;j,,05:iN7, Helianthate: red- 

 brown crystals, m.p. : darkening at 200° (dec.), Trihydro- 

 chloride: [a]n-^ -91° (c 1.0 in water). 



NH— C— NH, 



