Pfizer Handbook of Microbial Metabolites 



56 



maining two hydroxyls by fatty acids as their coenzyme A esters. 

 The phosphate group is then displaced by a choline phosphate 

 group contributed by a coenzyme, cytidine diphosphocholine : 



O 



II 

 CH2— O— C— R 



O CH3 



CH— O— C— R + CH3- 



NHo 



CH2 



O 



T 



-0— P— OH 

 OH 



Diglyceride 

 Phosphate 



-N— CH2— CH2— O— P- 



I© I 



CH3 eo 



o 



T 

 -0— p— o- 



OH 



-CH2 



Cytidine-5'-diphosphatecholme 



/""N 



O 



/On 



OH OH 



CH2— O— C— R 



O 

 CH— O— C— R 



+ Cytidine Phosphate 



CH2 



O 



T 



CH3 



-CH2— N— CH3 



©I 



CH3 



-0— P— O— CH2 



00 

 The mechanism for cephalin formation is probably similar. 



67 Formic Acid, CHoOo, colorless liquid, b.p. 100.5°, n,,-" 1.3714. 



HCOOH 



Pseiidomonas forniicans n. sp., etc. 



See the reference below for earlier work. 



Irving P. Crawford, /. Bacteriol. 68 734 (1954). 



68 Oxalic Acid, C.H0O4 (Dihydrate), colorless tablets, m.p. 101°. 



HOOC— COOH 



Aspergillus niger, Penicilliuni oxalicinn, Citromyces 

 spp., many other fungus species and most lichens. 



It occurs as the calcium salt in most lichens and higher 

 fungi, but occasionally also as the free acid. 



