Pfizer Handbook of Microbial Metabolites 98 



Idem., "Carotenoids," Chemical Publishing Co., Inc., New 

 York, N. Y. 1954, p. 108 etc. 



J. Bonner, A. Sandoval, W. Tang and L. Zechmeister, Arch. 

 Biochem. 10 113 (1946). 



167 8-Carotene, C40H56, fine orange to red needles, m.p. 140.5°, U.V. 

 488, 456, 430, 280 m^u in isooctane. 

 Proposed structure: 



Cantharellus cibarius, Neurospora crassa (mutants), 

 Staphylococcus aureus 



Harry Willstaedt, Svensk Kem. Tidskr. 49 318 (1937). 



Ben Sobin and Grant L. Stahly, /. Bacterial. 44 265 (1942). 



J. W. Porter and M. M. Murphy, Arch. Biochem. and 

 Biophys. 32 21 (1951). (Isolation) 



Francis Haxo, Biol. Bull. 103 268 (1952). 



168 Lycopene ( Solanorubin, Rhodopurpurene ) C4oH,-g, brownish red 

 to carmine crystals, m.p. 174°, U.V. 446, 474, 506 m^^ in 

 petroleum ether. 



Phycomyces Make slee anus, certain Cantharellus spp., 

 Neurospora^ crassa. Micrococcus tetragenus (pink type), 

 Anthurus aserioformis, Allomyces javanicus, Rhodotorula 

 glutinis, R. rubra, R. sanniei, Corynebacterium michiga- 

 nense, C. diphtheriae, Mycobacterium phlei. Staphylococ- 

 cus aureus, Coleosporium senecionis, Sarcina aurantiaca 



Harry Willstaedt, Svensk. Kem. Tidskr. 49 318 (1937). 



Francis Haxo, Arch. Biochem. 20 400 (1949). 



P. Karrer, C. H. Eugster and E. Tobler, Helv. Chim. Acta 

 33 1349 (1950). (Synthesis) 



T. W. Goodwin, Ann. Rev. Biochem. 24 497 (1955). 



Synnove Liaaen Jensen, Germaine Cohen-Bazire, T. O. M. 

 Nakayama and R. Y. Stanier, Biochim. et Biophys. Acta 29 

 477 (1958). 



