137 



Other Macrolides 



Streptoviyces erythreus 



Paul F. Wiley, Richard Gale, C. W. Pettinga and Koert 

 Gerzon, /. Am. Chetn. Soc. 79 6074 (1957). (Structure and 

 isolation) 



278 Erytliromycin B, CinHcyOj.^N, colorless crystals, m.p. 198°, [alo"^ 

 -78° (c 2 in ethanol). 



Desosamine ' 



Cladinose 



CHs Cms CHs 



Streptomyces erythreus 



Paul F. Wiley, Max V. Sigal, Jr., Allidene Weaver, Rosema- 

 rie Monahan and Koert Gerzon, /. Am. Chem. Soc. 79 6070 

 (1957). (Structure) 



C. W. Pettinga, W. M. Stark and F. R. Van Abeele, ibid. 76 

 569 (1954). (Isolation) 



279 Erythromycin (Ilotycin, Erythrocin), CojHgyOiaN, white needles, 

 m.p. 136-140°, [aW -78° (c 1.99 in alcohol). 



Desosamine" 



Cladinose 



Erythronolide 



Streptomyces erythreus 



R. K. Clark, Jr. Antibiotics and Chemotherapy 3 663 

 (1953). (Isolation) 



Paul F. Wiley, Koert Gerzon, Edwin H. Flynn, Max V. 

 Sigal, Jr., Allidene Weaver, U. Carol Quarck, Robert R. Chau- 



