Pfizer Handbook of Microbial Metabolites 



138 



vette and Rosemarie Monahan, J. Am. Chem. Soc. 79 6062 



(1957). (Structure) 



280 PA-108, C,.isH6:hOi4N, colorless solid, m.p. 121-123°, [^W -36.8° 



(c 1 in chloroform). 



A macrolide antibiotic. 



Streptoviyces sp. 



K. Murai, B. A. Sobin, W. D. Celmer and F. W. Tanner, 

 Antibiotics and Chemotherapy, 9 485 (1959). 



281 PA-148, C3sH6r,Oi-,N, colorless amorphous solid, m.p. 115-118°, 



[a]v-^ -69.3° (c 0.5 in methanol). 



A macrolide antibiotic. 



Streptomyces sp. 



K. Murai, B. A. Sobin, W. D. Celmer and F. W. Tanner, 

 Antibiotics and Chemotherapy, 9 485 (1959). 



282 Carbomycin B, C4.Hf570i-,N, colorless plates, m.p. 141-144° 



(dec), Hydro'chloride 164-166° (dec), [oc],,-' -35° (c 2.0 

 in chloroform). 



CH3 



OCOCH2CH(CH3)2 

 CH3 



Isovaleryl 

 Mycarose 



CH 



Streptomyces halstedii 



F. A. Hochstein and Kotaro Murai, /. Am. Chem. Soc. 76 

 5080 (1954). (Isolation) 



R. B. Woodward, Angexv. Chem. 69 50 (1957). (Struc- 

 ture) 



283 Carbomycin (Magnamycin), C42H(;70,,jN, colorless laths, m.p. 

 212-214° (dec), [aW -58.6° (c 1 in chloroform). 



Carimbose 



CHO CH 



J /O 



CH3 



OCOCH2CH(CH3)2 

 CH3 



Isovaleryl 

 Mycarose 



OH 



N(CH3)2 



OCOCH3 



Mycaminose 



