Pfizer Handbook of Microbial Metabolites 



140 



Raymond Paul and Serge TchelitchefF, Bull. soc. chim. 

 France 442, 734 (1957). 

 Idem., ibid., 150 (1960). 



290 Tylosin, C45H-9O17N, colorless crystals, m.p. 128-132°, [ajn'" 



—46° (c 2 in methanol). 



A macrolide antibiotic, containing the sugars mycarose 

 and mycaminose. Also has an a, /?, y, 8-unsaturated car- 

 bonyl system. 



Streptomyces fradiae 



R. L. Hamill, M. E. Haney, Martha C. Stamper and Paul 

 Wiley, Abstr. Atlantic City Meeting, Am. Chem. Soc, Septem- 

 ber, 1959. (To be published) 



J. M. McGuire, W. S. Boniece, W. A. Daily, C. E. Higgens, 

 M. M. Hoehn, W. M. Stark, W. B. Sutton, J. Westhead and 

 R. N. Wolfe- (To be published) 



291 Angolamycin, C49_5oHs7_9iOisN, colorless crystals, m.p. 165— 



168°, [aln'^ -64° (c 1.3 in chloroform). 



A macrolide antibiotic apparently similar to carbomy- 

 cin, but with characteristic sugars. 



Streptoviyces eurythermus 



R. Corbaz, L. Ettlinger, E. Gaumann, W. Keller-Schierlein, 

 L. Neipp, V. Prelog, P. Reusser and H. Zahner, Helv. Chim. 

 Acta 38 1202 (1955). 



292 Miamycin, colorless crystals, m.p. 221° (dec), [a]i)^^ 

 1.0 in 0.02 N hydrochloric acid). 



18° (c 



