Pfizer Handbook of Microbial Metabolites 152 



Roger P. Frohardt, Henry W. Dion, Zbigniew L. Jukabow- 

 ski, Albert Ryder, James C. French and Quentin R. Bartz, 

 /. Am. Chem. Soc. 81 5500 (1959). 



E. E. Van Tamelen and V. Haarstad, J. Am. Chem. Soc. 82 

 2974 (1960). (Revised structure) 



316 3-[2-(3,5-Dimethyl-5-acetoxy-2-oxocyclohexyl)-2-hydroxyethyl] glu- 

 tarimide (4-Acetoxycycloheximide, E-73), CiyHssOgN, col- 

 orless crystals, m.p. 140°, [<x]d~^ —8.8° (c 1.0 in methanol.) 



Streptomyces alhulus 



Two diastereoisomers of cycloheximide were isolated 

 from the same broth. Fungicidin and two unknown com- 

 pounds also were isolated. 



Koppaka V. Rao and Walter P. Cullen, J. Am. Chem. Soc. 

 82 1127 (1960). (Isolation) 



Koppaka V. Rao, ibid. 82 1129 (1960). (Structure) 



317 Glauconic Acids. 



Glauconic Acid I, CigHoyO^, colorless crystals, m.p. 

 202°, optically inactive. 

 Proposed structure: 



CH3 r ' CH2CH2CH3 



/ — V^"^ 



o o 



and 



Glauconic Acid II, CisHooOe, colorless crystals, m.p. 

 186°, optically inactive. 



Proposed structure: 



3 

 \ 



CH3 ^"' CH2CH2CH3 



/^\ 



O O ? 



/ \C"^ 



o o 



