Pfizer Handbook of Microbial Metabolites 198 



399 Mellein (Ochracin), C10H10O3, colorless prisms, m.p. 58°, [a]D 



-124.86° ([aW- -108.i5° in chloroform). 



O 



II 



^CH— CH3 

 CH2^ 



Aspergillus melleus Yugawa, A. ochraceus 



Eijiro Nishikawa, /. Agr. Chem. Soc. Japan 9 772 (1933). 

 (Isolation) (Chem. Abstr. 28 2751) 



Teijiro Yabuta and Yusuke Sumiki, ibid. 9 1264 (1933). 

 (Isolation) (Chem. Abstr. 28 2350) 



John Blair and G. T. Newbold, J. Chem. Soc, 2871 (1955). 

 (Structure) 



It is interesting to note that a similar compound : 



O 



OH I 



/ > 



^CH— CH3 

 CH3O \h/ 



has been isolated from carrots which had developed a 

 bitter taste during cold storage. 



Ernest Sondheimer, J. Am. Chem. Soc. 79 5036 (1957). 

 (Isolation") 



400 3,5-Dimethyl-6-oxyphthalide, Ci^HioOg, colorless needles, m.p. 



156-158°. 



Penicillium gladioli 



