203 Phenols and Phenol Ethers (General) 



414 Alternariol, Ci4Hj„0-,, colorless needles, m.p. 350° (dec.) 



and 



415 Alternariol Methyl Ether, CisHjoO.-,, colorless needles, m.p. 267° 



(dec). 



Q / OH 



CH3 OH ^ 



The methyl ether is at one of the positions indicated. 

 Alternaria tenuis 



The yield was about V2 g. per Uter. 



H. Raistrick, C. E. Stickings and R. Thomas, Biochem. J. 

 55 421 (1953). 



416 Altertenuol, C14H10O6, buff -colored rods, m.p. 284° (dec. and 



subl.). 



Forms a triacetate and a trimethyl derivative. Prob- 

 ably related to alternariol. 



Alternaria tenuis 



T. Rosett, R. H. Sankhala, C. E. Stickings, M. E. U. Taylor 

 and R. Thomas, Biochem. }. 67 390 (1957). 



417 Sorbicillin, Ci4H|,.03, orange plates, m.p. 113° (remelting at 



129°). 



CH. ?" ? 



"° CH, 



Penicillium notatum Westhng 



Donald J. Cram and Max Tishler, /. Am. Chem. Soc. 70 

 4238 (1948). (Isolation from Clinical Sodium Penicillin) 



Donald J. Cram, ibid. 70 4240 (1948). (Structure) 



Besides sorbicillin several other compounds were iso- 

 lated from careful investigation of a sample of early clini- 

 cal sodium penicillin. In view of the source it is hard to 

 say which of these may be considered true metabohtes. 

 The other compounds were: 

 Tiglic Acid, C.^HsOo, m.p. 63° 



d-a-Methylbutyric Acid, C5H10O2 b.p. 175°, [ajn'" +15.2° 

 Furoic Acid, m.p. 129° 



