Pfizer Handbook of Microbial Metabolites 208 



431 Bromogriseofulvin, Ci7Hi706Br, colorless crystals, m.p. 204°. 



O OCH3 



OCH3 II I 



I C C=CH 



\ / \ 



c c=o 



/ \ / 



CH3O I O CH — CH2 



Br I 



CHs 



On the proper medium bromogriseofulvin generally can 

 be produced by the same molds which produce griseoful- 

 vin. 



J. MacMillan, J. Chem. Soc, 2585 (1954). (Isolation) 



432 Dechlorogriseofulvin, Ci^HigOg, colorless needles, m.p. 179- 



181°, [alo" +390° (c 1 in acetone). 



OCH3 



?'"7 C=CH 



CH3O CH— CH2 



CH3 



Penicillium griseofulvum Dierckx, P. janczewski Zal. 



J. MacMillan, Chem. and Ind., 719 (1951). 



Idem., J. Chem. Soc, 1697 (1953). 



D. H. R. Barton and T. Bruun, /. Chem. Soc, 603 (1953). 



433 Mycophenolic Acid, C17H20O6, colorless needles, m.p. 141°. 



CH3 



I 

 HOOCCH2CH2— C=CH— CH 



CH3O 



_rM>0 



Penicillium brevi-compactum Dierckx 



C. L. Alsberg and O. F. Black, Bull. U. S. Bur. PI. Ind., 

 No. 270 (1913). (Isolation) 



Percival Walter Clutterbuck, Albert Edward Oxford, Harold 

 Raistrick and George Smith, Biochem. }. 26 1441 (1932). 



