Pfizer Handbook of Microbial Metabolites 



2IO 



Aspergillus glaucus, other aspergilli 



H. Raistrick, Robert Robinson and A. R. Todd, /. Chem. 

 Soc, 80 (1937). 



Adolfo Quilico, C. Cardani and G. Stagno d'Alcontres, Gazz. 

 chim. ital. 83 754 (1953). (Structure) 



437 Picrolichenic Acid, Co-H.^hOy, colorless crystals, m.p. 178° (dec). 

 Proposed structure: 



CH3O 



CH3CH2CH2CH2CH2 



OH 

 COOH 



CH2CH2CH2CH2CH3 



Pertusaria amara (Ach.) Nyl., Variola amara (Ach.) 



The yield was 5-10 S^ of the dry weight of the lichen. 



H. Erdtman and C. A. Wachtmeister, Chem. and Ind., 1042 

 (1957). 



Carl Axel Wachtmeister, Acta Chem. Scand. 12 147 (1958). 

 (Structure) 



438 a-Tocopherol (Vitamin E), Co^H-.^Oo^ viscous oil, b.p. 200-220° 

 (0.1 mm.), Ud'' 1.5045, U.V. max. 294 m/x. 



HO 



CHs 



CH3 



CH; 



/^ (CHo)3— CH— (CHo)3— CH— (CHsls— CH— CHs 



^O^ CH3 CH3 CH3 



CH3 



Identified in about a dozen varieties of chlorophyll-con- 

 taining bacteria by paper chromatographic comparisons. 

 (Not isolated.) 



J. Green, S. A. Price and L. Gare, Nature 184 1339 (1959). 



439 Chartreusin (Antibiotic X-465A), C;^2H320l4, greenish yellow 

 crystals, m.p. 184-186°, [aW^ +132° ±6° (c 0.2 in pyri- 

 dine). 



