Pfizer Handbook of Microbial Metabolites 224 



Yasuhiko Asahina and Michio Hiraiwa, Ber. 70B 1826 

 (1937). (Synthesis) 



470 Fumarprotocetraric Acid, C22H16O12, colorless needles, m.p. 250— 

 260° (dec. from 230°). 



CH3 , CH2OOC— CH=CH— COOH 



COO I OH 



Cetraria islandica Ach., Cladonia rangiferina (L. ) 

 Web., CI. sylvatica (L.) Hoffm. 



Yasuhiko Asahina and Yaichiro Tanase, Ber. 67B 766 

 (1934). 



471 Sekikaic Acid, C22H26O8, colorless needles, m.p. 147° (dec). 



CH3CH2CH2 .COO. OH ^^^,. 



\ I COOH 



CH3O OH CH3O CH2CH2CH3 



Ramalina geniculata Hook et Tayl., R. calicaris Rohl, 

 and R. intermediella Wain. 



The yield was about 1 % . A little d-usnic acid also was 

 present as well as ramalinolic acid. 



Yasuhiko Asahina and Masaichi Yasue, Ber. 68B 132 

 (1935). (Synthesis) 



472 Sphaerophorin, C23H28O7, colorless crystals, m.p. 137°. 

 CH3 



CH3O OH I COOH 



CHoCHoCH^CHoCHoCHiCHs 



Sphaerophorus fragilis Pers., S. coralloides Pers., S. mel- 

 anocarpus 



