Pfizer Handbook of Microbial Metabolites 240 



B. G. Engel and W. Brzeski, Helv. Chim. Acta 30 1472 



(1947). 



492 Terreic Acid, C7H6O4, pale yellow, large, glistening plates, m.p. 

 127-127.5°, [aln" -28.6° (c 1 in 50% methanol-benzene). 

 Sublimes. 



Aspergillus terreus grown in a glucose and corn-steep 

 liquor-cottonseed meal medium. 



H. M. Florey, E. Chain, N. G. Heatley, M. A. Jennings, A. G. 

 Sanders, E. P. Abraham and M. E. Florey, "Antibiotics," Ox- 

 ford University Press, London, 1949 Vol. I p. 388. 



Murray A. Kaplan, Irving R. Harper and Bernard Heine- 

 mann. Antibiotics and Chemotherapy 4 746 (1954). Yield 

 138 g. from 200 liters. 



J. Sheehan, W. Lawson and R. Gaul, J. Am. Chem. Soc. 

 80 5536-5538 (1958). (Structure) 



493 4-Methoxytoluquinone (Coprinin), CgHgOg, yellow spangles, 

 m.p. 175°. 



CH3 ? 



OCH3 



Coprinus similis B. and Br., Lentinus degener Kalchbr. 

 grown on a Czapek-Dox medium, containing glucose and 

 corn-steep solids. 



Marjorie Anchel, Annette Hervey, Frederick Kavanagh, 

 Jerome Polatnick and WUliam J. Robbins, Proc. Nat. Acad. 

 Sci. U. S. 34 498 (1948). (Isolation) 



R. B. Woodward, Franz Sondheimer, David Taub, Karl 

 Heusler and W. M. McLamore, /. Am. Chem. Soc. 74 4234 

 (1952). (Synthesis) 



