Pfizer Handbook of Microbial Metabolites 276 



rated into four components; rhodomycin A, isorhodomycin A, 

 rhodomycin B and isorhodomycin B. The first three were iso- 

 lated in the crystalline state. These substances contained nitro- 

 gen, and, on mild acid hydrolysis, yielded an amino sugar, rho- 

 dosamine, CgHi703N, plus the aglycones (rhodomycinones, 

 isorhodomycinones ) . 



The same organism has yielded a number of other pigments 

 which do not contain nitrogen. These also have been desig- 

 nated rhodomycinones. Three of these, ^, e and iso-e have been 

 obtained crystalline. It has been reported (no experimental 

 details) that a y-rhodomycinone and six other rhodomycinones 

 have been isolated "in substance" and that three others have 

 been demonstrated by paper chromatography. The rhodomy- 

 cinones seem to resemble the pyrromycinones, quinocyclines, 

 cinerubins and rutilantinone. 



596 Rhodomycin A (Hydrochloride), C20H29O7NHCI, fine, dark red 



needles, m.p. 193° (dec.) (preheated block). 



Hans Brockmann and Use Borchers, Chem. Ber. 86 261 

 (1953). 



597 Isorhodomycin A (Hydrochloride), CooHsgOgNHCl (proposed), 



m.p. 220°, [a]606-76o'' +268 ±30° (c 0.1 in methanol). 



Hans Brockmann and Peter Patt, Chem. Ber. 88 1455 

 (1955). 



598 Rhodomycin B (Hydrochloride), C19H27O7NHCI, red prisms, 



m.p. 180°, [a]606-76o'' +174 ±10° (c 0.05 in methanol). 



An isorhodomycin B also was present. 



Hans Brockmann and Peter Patt, Chem. Ber. 88 1455 

 (1955). 



599 ^-Rhodomycinone, C2oHi40g (proposed), dark red needles, m.p. 



225°. 



Hans Brockmann and Burchard Franck, Chem. Ber. 88 

 1792 (1955). (Isolation) 



Hans Brockmann and P. Boldt, Naturwissenschaften 44 616 

 (1957). (Revised empirical formula) 



600 €-Rhodomycinone, C2iH220g, thick red prisms, m.p. 185° (dec. 



at 208°) 



and 



601 £ -Isorhodomycinone, C20H20O9, dark red leaflets, m.p. 245° 



(dec). 



