Pfizer Handbook of Microbial Metabolites 296 



Coprinus comatis Gray 



Paul Heinz List, Arch. Pharm. 291 502 (1958). 



654 Acetylcholine, C7H17O3N, colorless, hygroscopic powder. 



(CHslsN— CH2CH2OCOCH3 



® 



Streptobacteriuvi plantarum 



Acetylcholine is produced also by the ergot fungus, 

 Claviceps purpurea, and probably by many other micro- 

 organisms. 



Yield: about 160 y per milUUter from the first organ- 

 ism above. 



Adolf Wacker, Adolf Roth, Heinz Sucker and Otto Dann, 

 Ann. 601 202 (1957). 



655 Spermidine, C7H19N3, unstable oil, b.p. 128° (14 mm.). 



H2N(CH2)3NH(CH2)4NH2 



Yeast, Neurospora crassa 

 Occurs as the phosphate. 



H. Tabor, S. M. Rosenthal and C. W. Tabor, Federation 

 Proc. 15 367 (1956). 



Ronald C. Greene, J. Am. Chem. Soc. 79 3929 (1957), 



656 ^-Phenylethylamine, CgHuN, liquid, b.p. 196-198°. 



/ V-CHsCHzNHz 



Boletus edulis, B. luteus, Claviceps purpurea, Polyporus 

 sulfureurS, Marasmius peronatus, Phlegmaciuni melliolus, 

 Nematoloma fasciculare, Pholiota mutabilis 



C. Reuter, Z. physiol. Chem. 78 167 (1912). 



Werner Keil and Hans Bartmann, Biochem. Z. 280 58 

 (1935). 



Elard Stein von Kamienski, Planta 50 335 (1958). 



P. H. List, Planta Med. 6 424 (1958). 



657 Tyramine, CsHj^ON, colorless crystals, m.p. 164°. (Picrate), 



m.p. 206°. 



HO—/ V-CH2CH,,NH2 



Coprinus comatis Gray, Claviceps purpurea 

 Paul Heinz List, Arch. Pharm. 291 502 (1958). 



