297 Amines 



658 Muscarine, CgHigOoN, white crystals, Hydrochloride [a]u^° 

 + 1.57° (in water). 



Amanita muscaria 



F. Kogl, C. A. Salemink, H. Schouten and F. Jellinck, Rec. 

 trav. chim. 76 109 (1957). (Structure) 



E. Hardegger and F. Lohse, Helv. Chim. Acta 40 2383 

 (1957). (Synthesis and configuration) 



P. J. Fraser, Brit. J. Pharmacol. 12 47 (1957). (Pharma- 

 cology) 



659 Muscaridine, CgHooOoNCl, isolated as the chloroaurate, 



CgHooAuCl^O.N, " m.p. 129-131° (dec), [aW +20.5° 

 ±0.5° (c 8.3 in water). 



CI® CH3 



© I 

 CH3— N— CH2— CH2— CHo— CH— CH— CH3 



I I I 



CH3 OH OH 



Amanita muscaria L. 



F. Kogl, C. A. Salemink and P. L. SchuUer, Rec. trav. 

 chim. 79 485 (1960). (Isolation) 



C. A. Salemink and P. L. SchuUer, ibid. 79 278 (1960). 

 (Synthesis) 



660 Spermine, C10H26N4, deliquescent, C02-absorbing crystals. 



Phosphate: m.p. 230-234° (dec). 



H2N(CH.2)3NH(CH2)4NH(CH2)3NH2 



Yeast, Neurospora crassa 

 Occurs phosphorylated. 



H. Tabor, S. M. Rosenthal and C. W. Tabor, Federation 

 Proc. 15 367 (1956). 



Ronald C. Greene, J. Am. Chem. Soc. 79 3929 (1957). 



661 Bufotenin, CioHigONo, colorless crystals, m.p. 146°. 



HO 



-CH2CH2N(CH3)2 



Oj 



H 



