323 Amino Acids and Related Compounds 



James A. Moore, John R. Dice, Ernest D. Nicolaides, Roger 

 D. Westland and Eugene L. Wittle, /. Am. Chern. Soc. 7(i 2884 

 (1954). (Synthesis) 



C. Chester Stock, H. Christine Reilly, Sonja M. Buckley, 

 Donald A. Clarke and C. P. Rhoads, Nature 173 71 (1954). 



John Ehrlich, Lucia E. Anderson, George L. Coffey, Arthur 

 B. Hillegas, Mildred P. Knudsen, Harold J. Koepsell, Dorothy 

 L. Kohberger and Julian E. Oyaas, ibid. 173 72 (1954). 



Quentin R. Bartz, Carole C. Elder, Roger P. Frohardt, Salva- 

 tore A. Fusari, Theodore H. Haskell, Doris W. Johannessen and 

 Albert Ryder, ibid. 173 72 (1954). (Isolation) 



679 L-Proline, C.^HciOoN, colorless crystals, m.p. 220-222° (dec.) 



(rapid heating), [x],,-"' —80° (c 1.0 in water). 



CH. — CH2 



CH2 CH— COOH 



H 



Widely distributed. 



680 L-GIutamic Acid, C-,H.,04N, colorless crystals, m.p. 247° (dec), 



[a]n--* +31.4° (c 1 in 6 N hydrochloric acid). 



HOOC— CH2— CHo— CH— COOH 



NH2 



Micrococcus varians 



A 17% molar yield (from glucose) was reported. 

 Toshinobu Asai, Ko Aida, Kunio Oishi, Bull. Agr. Chem. Soc. 

 (Japan) 21 134 (1957). 



681 L-Glutamine, C.-jHjoO^N^, colorless crystals, m.p. 185° (dec), 



[a]ir' +5.9° (c 4.0 in water). 



O 



H ,N— C— CH2— CH2— CH— COOH 



i 

 NH2 



Widely distributed. 



682 L-Valine, C-,Hi,O.N, colorless crystals, m.p. 315° (dec.) (closed 

 capillary). Sublimes, [a]ir'' +14°(c0.9in water). 



CH3 



\ 



CH— CH— COOH 



/ I 



CH3 NH2 



