Pfizer Handbook of Microbial Metabolites 326 



692 L-Leucine, CcHj-iOMN, colorless crystals, m.p. ~295° (dec.) 



(sealed tube") (subl. from 140°), [a],,-' -11° (c 2.0 in 

 water). 



CH3 



\ 



CH— CH2— CH— COOH 



/ I 



CH3 NH2 



Widely distributed. 



693 L-Isoleucine, CeHi.jO^N, colorless crystals, m.p. 284° (dec.) 



(subl. from 160°), [a],r" +11° (c 3.0 in water). 



CH3— CH2— CH— CH— COOH 



1 I 

 CH3 NH, 



Widely distributed. 



694 L-a-Aminoadipic Acid, C(jHii04N, white crystals, m.p. 206° 



(dec). 



HOOC— CH,CH,CH,CHCOOH 



NH, 



Aspergillus oryzae 



Also a component of several antibiotics. 



Emmanuel Windsor, /. Biol. Chem. 192 595 (1951). 



695 L-Lysine, C,jH,40^.No. white needles, m.p. 224°. 



H,NCH,CH2CH2CH,CHCOOH 



NH.. 



Ustilago maydis PRL 1092 



The yield was 200-300 mg. per liter of free lysine in the 

 broth as determined by a bioassay (not isolated). 



M. Richards and R. H. Raskins, Can. J. Microbiol. 3 543 

 (1957). 



696 L-Arginine, C,jH,40oN4, colorless crystals (Dihydrate), m.p. 



245° (dec.) (browning above 200°), [a],,-" +13° (c 3.5 

 in water). 



NH 



H N— C— NH— CH2— CH,— CH .— CH— COOH 



I 

 NHs 



Widely distributed. 



