Pfizer Handbook of Microbial Metabolites 330 



Claviceps purpurea (Fries), Tul. Coprinus comatus, 

 Mycobacterium tuberculosis 



C. Tanret, J. pharm. chim. 30 145 (1909). 



H. Heath and Jennifer Wildy, Biochem. J. 64 612 (1956). 

 (Biosynthesis) 



Paul Heinz List, Arch. Pharm. 290 517 (1957). 



Dorothy S. Genghof, Bad. Proc, 190 (1960). 



709 L-Tryptophan, CiiHi^O^,N2, colorless crystals, m.p. 289° (dec.) 

 (rapid heating), [ix]i,-'^ —31.5 (c 1.0 in water). 



CH2— CH— COOH 



CO 



NH2 



H 

 Widely distributed. 



710 Amino Acid from Lactarius helvus, CuHiyOaNo, colorless crys- 

 tals, yellowing near 200° and darkening to 300°. Molecu- 

 lar weight 251 by isothermal distillation. Adds 2 H^ and 

 2 Bro. 



Partial structure: 



HOOC— CH CH— COOH 



NH,. ^ NH2 



C7H10 



C 



\^ 



containing C= and C=C 



/ 

 C 



Lactarius helvus 



Ateushi Komamine and Artturi Virtanen, Acta Chem. Scaiid. 

 13 2141 (1959). 



J. Casimir and A. I. Virtanen, ibid. 13 2139 (1959). (Iso- 

 lation ) 



711 Elaiomycin, C,..iHo,;0;!N._,, pale yellow oil, [a],,"' +38.4° (c 2.8 in 

 absolute ethanol). 



O OH 



T I 



CH3(CH2)5CH=CH— N=N— CH— CH— CH3 



CH0OCH3 

 Streptomyces hepaticus 



