Pfizer Handbook of Microbial Metabolites 350 



Serratia species 



Yields as high as 8 g. per liter have been reported. 

 Hydrolysis gives L-serine and ( — )-3-oxydecanoic acid. 

 The latter acid also has been found in conjugation with 

 rhamnose and with other amino acids (see Viscosin). 



N. J. Cartwright, Biochem. J. 60 238 (1955). 



Idem., ibid. 67 663 (1957). (Structure) 



724 8-(a-Aminoadipyl) cysteinylvaline, C14H25O6N3S. 



CH3 CH3 



\ / 

 CH 



O CH,— SH 



HOOC— CH— CHo— CHo— CHo— C— NH— CH— C— NH— CH— COOH 



NH2 O 



Fenicillium chrysogenum 



This tripeptide was isolated from the mycelium of the 

 penicillin-producing mold. It may be a penicillin precur- 

 sor since cyclization in the proper way would yield syn- 

 nematin-B (cephalosporin-N) which differs from penicil- 

 lin only in its side-chain. Synnematin never has been 

 isolated from P. chrysogenum, however. 



H. R. V. Arnstein, D. Morris and E. J. Toins, Biochim. et 

 Biophys. Acta 35 561 (1959). 



725 Alazopeptin, Ci.^Ho^OeN^, no definite m.p., [a]i,-' +9.5° (c 4.7 in 



water). 



A peptide containing 1 mole of a-alanine and 2 moles 

 of 6-diazo-5-oxoaminohexanoic acid (DON) or an isomer. 



Streptomyces griseoplanus 



S. E. DeVoe, N. E. Rigler, A. J. Shay, J. H. Martin, T. C. 

 Boyd, E. J. Backus, J. H. Mowat and N. Bohonos, "Antibiotics 

 Annual 1956-1957," Medical Encyclopedia, Inc., New York, 

 p. 730. 



726 Antibiotic I.C.I. 13,959. 



Acid hydrolysis yielded: 

 a-Aminoisobutyric Acid 



CH3 COOH 



CH3 NH2 



