Pfizer Handbook o£ Microbial Metabolites 



352 



Streptomyces spp. 



R. W. Rivett and W. H. Peterson, J. Am. Chem. Soc. 69 

 3006 (1947). (Isolation) 



Edward E. Smissman, Robert W. Sharpe, B. F. Aycock, 

 Eugene E. van Tamelen and W. H. Peterson, ibid. 75 2029 

 (1953). 



Eugene E. van Tamelen and Edward E. Smissman, ibid. 75 

 2031 (1953). 



Eugene E. van Tamelen, John R. Dyer, Herbert E. Carter, 

 Jack V. Pierce and Edward E. Daniels, ibid. 78 4817 (1956). 



730 Noformicin* (Sulfate), Ci7H3405Nio( 804)2, m.p. (Hydrochlo- 



ride) 265° (dec.). 



Hydrolysis yields glutamic acid, ammonia and two other 

 ninhydrin-positive compounds which are not ordinary 

 amino acids. 



Nocardia formica 



Dale A. Harris and H. Boyd Woodruff, "Antibiotics Annual 

 1953-1954," Medical Encyclopedia, Inc., New York, p. 609. 



731 Streptothricin, CooHj^qOoNs, platelets (Reineckate), m.p. 192-194° 



(Hydrochloride)' [a] d'' -51.3°. 



A basic polypeptide. Hydrolysis yields: 



L-/3-Lysine: 



H2NCH2CH2CH2CHCH2COOH 



NH2 



D-Gulosamine: 



H— C— OH 



I 

 H— C— NH2 



I 

 H— C— OH 



I 

 HO— C— H 



I 

 H— C 



Streptolidine: 



CH2OH 



C6H,2N403 



Several structures have been proposed for this moiety. 

 See C. Sweeley, Ph.D. Dissertation, Univ. of Illinois, 1955. 

 See entry 915 for structure. 



