353 



Polypeptides and Related Compounds 



732 



It may be identical with the amino acid known as roseo- 

 nine or ge amine. 



OH 



I 

 N CH— C— COOH 



II I I 



H2N— C CH2 CH2NH2 



\ / 

 N 

 H 



Carbon dioxide and ammonia also have been identified 

 in hydrolysates. 



Streptomyces lavendulae and other streptomyces species 



Selman A. Waksman and H. Boyd Woodruff, Proc. Soc. Exp. 

 Biol. Med. 49 207 (1942). (Isolation) 



Herbert E. Carter, Walter R. Hearn, Edwin M. Lansford, Jr., 

 A. C. Page, Jr., Norman P. Salzman, David Shapiro and W. R. 

 Taylor, /. Am. Chem. Soc. 74 3704 (1952). (Structure) 



H. E. Carter, R. K. Clark, Jr., Paul Kohn, John W. Rathrock, 

 W. R. Taylor, C. A. West, George B. Whitfield and Wilham G. 

 Jackson, ibid. 76 566 (1954). 



Koji Nakamishi, Tashito Ito and Yoshimasa Hirata, ibid. 76 

 2845 (1954). 



Eugene E. van Tamelen, John R. Dyer, Herbert E. Carter, 

 Jack V. Pierce and Edward E. Daniels, ibid. 78 4817 (1956). 



R. Colin, Ph.D. Dissertation, Gottingen, 1957. 



Roseothricins. 



A polypeptide antibiotic complex of the streptothricin 

 type. Acid hydrolysis of Roseothricin A yields /? -lysine 

 and roseonine (geamine) I in a 1:1 ratio, an isomer of 



OH 



I 

 N CH— C— COOH 



HC CH2 CH2NH2 



