Pfizer Handbook of Microbial Metabolites 360 



Herbert E. Carter, Carl P. SchafFner and David Gottlieb, 

 Arch. Biochem. and Biophys. 53 282 (1954). 



754 Staphylomycin Mj, CosHagOsNg (probable), m.p. 165-167° (dec), 



[a]D -190° ±2° (c 0.5 in ethanol). 



A neutral compound. Carbonyl group present. Gly- 

 cine and proline liberated on acid hydrolysis. Related to 

 PA 114A.* 



755 Staphylomycin S, C3g_39H47_4s09N6 (proposed, but see structure 



below), white crystals, m.p. 240-242° [a]i, -28.0° (c 1.0 

 in ethanol). 



A weak acid. Threonine, norvaline, a-aminobutryic 

 acid, phenylalanine and proline were produced on acid 

 hydrolysis. Related to PA 114B (or identical). 



Staphylomycin Mo. This third factor has not been ob- 

 tained pure. 



There appears to be a relationship between the staphy- 

 lomycin complex and streptogramin, etamycin, etc. 



Streptomyces sp. resembling S. virginiae 



H. Vanderhaeghe, P. Van Dijck, G. Parmentier and P. De 

 Somer, Antibiotics and Chemotherapy 7 606 (1957). 



The probable structure of one of the staphylomycins 

 recently was reported to be : 



♦Identical with PA 114A. 



