363 Polypeptides and Related Compounds 



:H3(CH )6— CH— CH2— CO— NH CH CO— NH— CH. CO NH CH CO— 



I I " I 



OH CH, CHo 



I 1 



CH OH 



/ \ 



CH3 CH:, 



NH— CH— CO— NH— CH— CO— NH— CH— COOH 



I I I 



CH CHOH CH2 



/ \ I I 



CH3 CHa CH3 CH 



/ \ 

 CH3 CH3 



Pseudomonas viscosa 



Mitsuyuki Kochi, Vincent Groupe, Leonora H. Pugh and 

 David Weiss, Bad. Proc, 29 (1951). 



Takashi Ohno, Shigeru Tajinia and Katsuyuki Toki, /. Agr. 

 Chem. Soc. Japan 27 665 (1953). 



Doki and Ohno (unpublished). Total structure determina- 

 tion. Reported by S. Otani in a lecture on polypeptide anti- 

 biotics in 1957. 



Takashi Ohno, Shigeru Tajima and Katsuyuki Toki, /. Agr. 

 Chem. Soc. Japan 27 665 (1953). 



760 Bottromycin (B-Mycin), C3sH57_r,i07_.sN7S, white amorphous ma- 

 terial, [a],;--' -14.2° (c 0.5 in 96%, ethanol). 



Bottromycin is a weakly basic polypeptide. Acid hy- 

 drolysis yields six ninhydrin-positive compounds. Two of 

 these are glycine and valine. Two others are new amino 

 acids : 



a-Amino-/3-phenylbutyric Acid 



CH CH— COOH 



CH3 NH2 



and 

 /3-(2-Thiazole)-/3-alanine 



CH— CHo— COOH 



I 

 NH2 



Streptomyces bottropensis 



