Pfizer Handbook of Microbial Metabolites 



370 



aspartic acid, glutamic acid, serine, threonine, glycine 

 and alanine. 



The structural evidence has been well summarized and 

 a partial structure postulated by R. Colin, Ph.D. Disserta- 

 tion, Gottingen, 1957. The partial structure is: 



NH NH2 



-C— NH— R^ 



O 



HOOC— C CH N 



I I II 



CH2 CH2 C 



I \m/ 



NHo ^^ 



NH2 



Streptomyces xanthophaeus , n.sp. 



Hans Brockmann and Burchard Franck, Naturwissenschaf- 

 ten 41 451 (1954). 



Hans Brockmann and Hans Musso, Chem. Ber. 87 1779 

 (1954). 



Idem., ibid. 88 648 (1955). 



774 Lavendulin (Helianthate), C49H63O18N13S (proposed), orange 



crystals, m.p. 212-220° (dec). 



A basic polypeptide. Positive FeCIs, Fehhng, biuret, 

 KMn04. Negative Molisch, Sakaguchi. 



Streptomyces sp. similar to S. lavendulae 



Albert Kelner and Harry E. Morton, J. Bad. 53 695 (1947). 

 (Isolation) 



Harry E. Morton, Proc. Soc. Exp. Biol. Med. 64 327 (1947). 



775 Echinomycin (X-948),* C-,„H„„Oi2Ni^,S2, granular, nearly color- 



less hygroscopic powder, m.p. 217°, [a]i> —310° (c 0.86 

 in chloroform). 



CH-CO NH— CH— CO— N - C— CO -N— CH— CO- O CH. 



/ \ 

 S CH, 



I I 



CH: S 



CH,— O— CO— CH— N— CO-C-N CO— CH NH-CO— CH 



II II 



CH CH, CH, CH, 



/ \_ I 



CH, 



CH, 



CO 



* Antibiotic X-1008 (unclassified) resembles echinomycin. 



