Pfizer Handbook of Microbial Metabolites 392 



G. Cheeseman and N. Berridge, Biochem. J. 71 185 (1959). 



820 Duramycin, colorless amorphous soUd, no definite m.p., Hydro- 



chloride: [a]rr' -6.4° (c 3.9 in water). 



Duramycin is a polypeptide, containing at least one 

 free amino group and several free carboxyl groups. Acid 

 hydrolysis yielded: lanthionine, ^-methyllanthionine, as- 

 partic acid, glutamic acid, glycine, valine, proline, phenyl- 

 alanine and possibly ornithine and hydroxyproUne. Du- 

 ramycin is related to, but distinct from, cinnamycin. 

 Streptomyces cinnamoneus f . azacoluta 

 Odette L. Shotwell, Frank H. Stodola, William R. Michael, 

 Lloyd A. Lindenfelser, Robert G. Dworschack and Thomas G. 

 Pridham, J. Am. Chem. Soc. 80 3912 (1958). 



821 Cinnamycin. 



A polypeptide containing (probably): glutamic acid, 

 aspartic acid, proline, phenylalanine, valine, arginine, 

 lanthionine and /3-methyllanthionine. 



Streptomyces cinnamoneus 



Robert G. Benedict, William Dvonch, Odette L. Shotwell, 

 Thomas G. Pridham and Lloyd A. Lindenfelser, Antibiotics 

 and Chemotherapy 2 591 (1952). 



Robert G. Benedict, Bot. Rev. 19 229 (1953). 



822 Matamycin, colorless crystals, m.p. 173° (dec), [ajn^" +36.6° 



(c 0.11 in methanol). 



An essentially neutral antibiotic of low solubility. 

 Analysis: C 43.95, H 4.06, N 14.45, S 13.57. Halogen- 

 free. Positive Fehlings, ToUens, permanganate, DNPH, 

 and (after hydrolysis) ninhydrin tests. Negative ferric 

 chloride and Sakaguchi tests. A hydrolysate contained: 

 cysteic acid, glycine, serine, alanine, arginine and two 

 other amino acids. 



Streptomyces matensis n. sp. 



P. Sensi, R. Ballotta and G. G. Gallo, Antibiotics and Chem- 

 otherapy 9 76 (1959). 



An inactive compound, "Compound I," evidently of 

 analogous structure was isolated from the same culture: 



823 Compound I, colorless crystals, m.p. 189° (dec), [aln'" +151.6° 



(c 0.1 in dioxane). 



Analysis: C 45.84, H 3.90, N 14.99, S 14.64. It may 

 be a dehydration product of matamycin. 



