409 Pyrans and Related Substances 



Gliiconoacetobacter roseum (fructose substrate) - 

 Isokojic acid was produced together with kojic acid and 



an unidentified substance. 



Ko Aida, Mitsuko Fujii and Toshinobu Asai, Proc. Japan. 



Acad. 32 600 (1956). 



867 Patulin (Clavacin, Clavatin, Claviformin, Penicidin, Expansine, 

 Mycoin), C7H6O4, colorless crystals, m.p. 111°. 



O 



o 



I 



OH 



Penicillium patuhnn Bainier (P. urticae), P. griseo- 

 fulvum, P. claviforme, P. expansum, P. melinii, P. equi- 

 num, P. novae-zeelandiae, P. leucopus, Aspergillus clava- 

 tus, A. terreus, A. giganteus, Gymrioascus spp. 



H. W. Florey, E. Chain, N. G. Heatley, M. A. Jennings, 

 A. G. Sanders, E. P. Abraham and M. E. Florey, "Antibiotics," 

 Oxford University Press, London, 1949, pp. 223-272. (Re- 

 views earher work) 



R. B. Woodward and Gurbakhsh Singh, J. Am. Chem. Soc. 

 72 1428 (1950). (Synthesis) 



868 5-Hydroxy-2-methylchromone, CioHgOa, yellow needles, m.p. 72- 

 76°. 

 Proposed structure : 



O 



CH3 

 Daldinia concentrica 

 D. C. Allport and J. D. Bu'Lock, J. Chem. Soc, 654 (1960). 



869 5-Hydroxy-2-niethylchromanone, C10H10O3, pale yellow needles, 

 m.p. 30-33°. 



OH O 



CH3 

 Daldinia concentrica 

 D. C. AUport and J. D. Bu'Lock, /. Chem. Soc, 654 (1960). 



