Pfizer Handbook of Microbial Metabolites 



430 



900 Biotin, CjoHifiOaNoS, colorless needles, m.p. 230-232° (dec), 

 [ale" +92° (c 0.3 in 0.1 N sodium hydroxide). 



HN 



HC- 



NH 



-CH 



CH2 CH— CHCHiCHoCH-COOH 



Torula utilis, other yeasts (occurs also in molds and 

 bacteria) 



Yields of 0.5-3.6 /xg. per gram of dry cell weight are ob- 

 tained from Torula utilis. 



Leland A. Underkofler and Richard J. Hickey, "Industrial 

 Fermentations," Chemical Pubhshing Co., Inc., New York, 

 1954 Vol. II, J. M. Van Lanen, Production of vitamins other 

 than riboflavin, chap. 6, pp. 191-216. (A review) 



901 Biotin- 1 -sulfoxide, Ci(,Hic04N2S, colorless crystals, m.p. 238- 

 243°, [a] I,-" -40° (in 0.1 N sodium hydroxide). 



HN NH 



CH CH 



CH2 CH— CH2CH2CH2CH2COOH 



Aspergillus iiiger 



Lemuel D. Wright and Emlen L. Cresson, /. Am. Chem. Soc. 

 76 4156 (1954). 



Lemuel D. Wright, Emlen L. Cresson, John Valiant, Don- 

 ald E. Wolf and Karl Folkers, ibid. 76 4160, 4163 (1954). 

 (Isolation and characterization) 



