465 Ergot Alkaloids 



943 Echinulin, CosHa^OsNg, white needles, m.p. 242°. 

 Probable structure: 



Aspergillus glaucus types, A. echinulatus, A. chevalieri 

 About 200 g. of pure material were obtained from 5 kg. 



of dry mycelium. Auroglaucin and flavoglaucin were 



isolated from the same source. 



A. Quilico and L. Panizzi, Ber. 76B 348 (1943). (Isolation) 

 Adolfo Quilico, Cesare Cardini and Franco Piozzi, Gazz. 



Chim. ital. 86 211 (1956). (Structure) 



Ziro Kitamura, Uzukiko Kurimoto and Matatsugu Yoko- 



yama, 7- Pharm. Soc. Japan 76 972 (1956). 



C. Cardani, G. Casnati, F. Piozzi and A. QuUico, Tetrahedron 



Letters No. 16 1 (1959). (Structure) 



h. ERGOT ALKALOIDS 



The constituents of the sclerotia of the fungus Claviceps 

 purpurea (Fries) TuL, a cereal parasite, have been exten- 

 sively studied. Some of the alkaloids are used in medicine 

 for their oxytocic properties and to relieve migraine. 



Ergocristine, ergokryptine and ergocornine (and their 

 isomers) constitute a closely related complex formerly 

 thought to be homogeneous and called ergotoxine. Be- 

 sides the alkaloids which are shown in the succeeding 



