Pfizer Handbook of Microbial Metabolites 



466 



pages, many other chemicals have been identified. 

 Among them are: 



Ergothioneine 



Histidine 



Tyrosine 



Betaine 



ChoUne 



Acetylcholine 



Cadaverine 



Putrescine 



Agmatine 



Histamine 



Tyramine 



Valine 



Leucine 



Ammonia 



Methylamine 



Trimethylamine 



Ethylamine 



n-Propylamine 



iso-Propylamine 



iso-Butylamine 



iso-Amylamine 



n-Hexylamine 



ytJ-Phenylethylamine 



Mannitol 



Clavicepsin 

 Ergosterol 

 Oils 



Lactic Acid 

 Succinic Acid 

 Oxalic Acid 

 Citric Acid 

 Formic Acid 

 Ethanol 

 Furfural 

 Acetaldehyde 

 Acetone 



Ergoflavine and 

 other pigments 



Careful work has shown that many of the alkaloids 

 produced in the natural state can be produced in artificial 

 culture as well/ -• ■' Total alkaloid yields of 1000-1500 

 mg. per liter of culture fluid have been obtained exclusive 

 of mycelial alkaloids.^ 



The conventional ergot alkaloids contain the lysergic 

 acid moiety I or isolysergic acid, the stereoisomer at posi- 

 tion 8. 



HOOC H 



^ A. Hofmann, R. Brunner, H. Kobel and A. Brack, Helv. Chim. 

 Acta 40 1358 (1957). 



'W. A. Taber and L. C. Vining, Can. J. Microbiol. 3 55 (1957). 

 3 Ervin Glaz, Acta Pharm. Hung. 25 11 (1955). 



I 



