Pfizer Handbook of Microbial Metabolites 498 



CH3 



HO CH.— CH O. 



CH3 f i CH3 



CH— CH2 OH 



CH3 



CH3 

 O / 



HO T CH2— CH 



CH3 'I I ^^^ 



K^ 



CH— CH, i OH 

 / O 



CH3 



The addition of sulfur across the diketopiperazine ring 

 in gliotoxin is interesting. 



986 Flavacol, CjoH^oONo, colorless needles, m.p. 147-149°. 



CH3 



/ 

 CH2— CH 



K 



CH3 II J C"' 



CH— CH 2 Oh 



/ 

 CH3 



Aspergillus flavus 



George Dunn, G. T. Newbold and F. S. Spring, /. Chem. Soc. 

 2586 (1949). (Synthesis) 



987 Aspergillic Acijcl, CjoHooOoN^, pale yellow needles, m.p. 97-99°, 

 [a]D-" +13.4° (c 1 in ethanol). 



CHs 



/ 

 H CH2— CH 



CH3 



CH3— CH. 



CH i OH 

 / O 



CH3 



Aspergillus flavus 



