Pfizer Handbook of Microbial Metabolites 



526 



In the same section the mediation of ATP in the forma- 

 tion of active carbon dioxide was seen: 



NH2 



ATP + CO2 



O O 



II T 



HO— C— O— P— O— CH 

 OH 



S.Xn'^ 



+ Pyrophosphate 



OH OH 



I Biotin phosphate 



NH2 



O 



II 



o 00 



II T T 



C— O— O— P— O— P— O— CH> .0 





HN 



1 

 CH- 



N 



I 

 -CH 



OH OH 



OH OH 



CH. CH2— (CH,)4— COOH 



\c/ i 



Enzyme 



Possible intermediate in 



formation of activated 



carbon dioxide 



Synthetic adenosyl-5'-phosphoryl carbonate has been pre- 

 pared.*^ 



The role of adenine nucleotide as the terminal or ac- 

 tivating nucleotide of transfer RNA in protein synthesis 

 was mentioned in the amino acid section. 



*^ B. K. Bachhawat, J. F. Woessner and M. J. Coon, Federation 

 Proc. 15 214 (1956). 



