19. 



Unclassified Metabolites 



1064 Aburamycin (M5-18903), yellow crystals, m.p. 163-165° (169- 



, 171°), [a]D'° +24.56° (c 1 in methanol) [aW -29° (c 0.5 

 in methanol). 



Absorbs 2 moles of Ho. Acetylates (m.p. acetate = 205- 

 207°). A weakly acidic antibiotic, apparent molecular 

 weight 1295. Aburamycin and M5-18903 appear to be 

 optical antipodes of the same compound. 



Streptomyces spp. 



Haruo Nichimura, Toshiaki Kimura, Katsuya Tawara, Kunio 

 Sasaki, Kiyoshi Nakajima, Noboru Shimaoka, Saburo Okamoto, 

 Masafumi Shimohira and Jun Isono, J. Antibiotics (Japan) 

 lOA 205 (1957). 



Richard M. Gale, Marvin M. Hoehn and Mack H. McCor- 

 mick, "Antibiotics Annual 1958-1959," Medical Encyclopedia, 

 Inc., New York, p. 489. 



1065 Actinobolin, Cj;iH2o-2206N2, amorphous hygroscopic white pow- 



der, [aW" (Sulfate) 4-54.5° (c 1 in water). 



An amphoteric antibiotic. Forms an acetate: m.p., 

 partial m. at 130°, resolidified 145°, dec. 263-266°, [a]^-^ 

 +58° (c 1 in water). Positive ninhydrin, ferric chloride, 

 KMn04, Tehlings, iodoform tests. Absorbs no hydrogen. 



Streptomyces sp. 



Theodore H. Haskell and Quentin R. Bartz, "Antibiotics An- 

 nual 1958-1959," Medical Encyclopedia, Inc., New York, p. 

 505. 



1066 Actinoleukin (C9Hi20HN2)n, colorless crystals, m.p. 191° (dec). 



Analysis: C 55.53, H 6.05, N 14.05 

 55.68, 5.98, 14.01 

 Negative biuret, ninhydrin, Tollens, Fehling. Positive 

 FeClg. 



