585 Unclassified Metabolites 



Motoo Shibata, Koichi Nakazawa, Akira Miyake, Michitaka 

 Inoue and Akira Akabori, Takeda Kenkyusho Nempo 16 32 

 (1957). (Chem. Ahstr. 52 10279e) 



1141 Cyanomycin, C15H10N0O0 (proposed), dark blue needles, m.p. 



128° (dec.)- 



A basic antibiotic pigment with pH-indicating prop- 

 erties, apparently distinct from other known pigments. 

 Aureothricin occurs in the same culture. 



Streptomyces strain No. 4738 



Masanao Funaki, Fumiyasu Tsuchiya, Kiyoharu Maeda and 

 Takeshi Kamiya, /. Antibiotics (Japan) llA 143 (1958). 



1142 Datemycin, C-,><Hlo-O^JN4, colorless powder, m.p. 197° (dec), 



[a]i/^ -43.7° (c 1 in water). 



U.V. maximum at 247 m/x. Negative ninhydrin 



6N HCl 



— — > positive ninhydrin. Negative Hopkins- 

 Cole, xanthoprotein, Sakaguchi, Millon, Elson-Morgan, 

 Molisch, Fehling, silver mirror tests. 



"M-14" strains 



Masahiko Kuroya and Yasuo Koyama, Japanese Patent 6648 

 (1959). 



1143 Desertomycin, C33H(;,,.yoOi4N, snow white crystals, m.p. 189°. 



Positive ninhydrin, C-methyl. Acetylates, hydrogenates, 

 decolorizes bromine or permanganate. 



A crystalline antifungal agent, flavofungin, has been 

 isolated from the same culture. 



Streptomyces flavofungini 



J. Ori and I. Behesi, Nature 181 908 (1958). 



J. tJri, R. Bognar and B. Varga, ibid. 182 401 (1958). 



1144 Diaporthin, C13HJ4O3, white crystals, m.p. 91.5-92.5° [ajn^^ +58° 



(c 1 in chloroform). 

 Endothia parasitica 

 A. Neelameghan, Hindustan Antibiotics 2 13 (1959). 



1145 Diplococcin, antibacterial substance elaborated by certain milk 



streptococci. In the same category as the sulfur-free 

 polypeptides, gramicidin and tyrocidine. Unlike these 

 polypeptides diplococcin contains arginine residues, shows 

 no tendency to crystallize and is obviously of greater mo- 

 lecular complexity. 



C 50.5, H 7.3, N 13.1, no sulfur. 



