6o9 Unclassified Metabolites 



1289 Taitomycin, yellow-brown powder, U.V. at 330, 420 m^x. 



C 53.57, H 4.87, N 9.50 ash 2.8. 



Positive Fehling and ninhydrin (acid hydrolysate). 



Streptoynyces afgJianensis 



Mitsuo Shimo, Tatsuji Shiga, Takashi Tomosugi and Ikuzo 

 Kamoi, /. Antibiotics (Japan) 12A 1 (1959). 



Takashi Tomosugi, Ikuzo Kamoi, Tatsuji Shiga and Mitsuo 

 Shimo, ibid. 12A 7 (1959). 



1290 Tardin, CnHir.Oa (proposed), pale yellow oil, [a]v^° —11.4° (in 



alcohol). 



Positive FeCl... Negative 2,4-DNPH. Hydrolyzes to an 

 acidic and a neutral fraction. 



PeniciUium tardum 



N. Borodin, F. J. Philpot and H. W. Florey, Brit. J. Exp. 

 Path. 28 31 (1947). 



1291 Terrecin, light yellow prisms, m.p. 219°. 



Analysis: C 51.89, H 3.51, N 3.8, CI 19.1. Alkali 

 soluble. Positive FeCl^. 



Aspergillus terrens 



Kazuo Iwata and Itiro Yosioka, /. Antibiotics (Japan) 3 192 

 (1950). 



1292 Thiactin, acid and alkali metal salts (previously identified as 



bryamycin). M.p. 220-234°, [a]n'' -68.5 -69.5° (c 1 

 in chloroform). 



Streptomyces hawaiiensis 



Bernard Heinemann, Irving R. Hooper and Martin J. Cron, 

 British Patent 790,521 (1958). 



1293 Thioaurin (Orosomycin, Antibiotic HA-9), CyHeOoN^So or 



Ci4H,.j04N4S4 (proposed), yellow crystals, m.p. 178-180°, 

 optically inactive. 



Strong U.V. at 232, 370 m^. Negative FeClg. 



Streptomyces sp. resembling S. lipmanii 



William A. Bolhofer, Roy A. Machlowitz and Jesse Charney, 

 Antibiotics and Chemotherapy 3 382 (1953). 



William Eisenman, P. Paul Minieri, Anthony Abbey, John 

 Charlebois. Mary Moncrieff-Yates and Neil E. Rigler, ibid. 3 

 385 (1953). 



1294 Thiomycin, golden yellow needles, m.p. 176-178° (dec). 



Resembles thioaurin somewhat. May be identical. 

 Analysis: C 49.61, H 5.50, N 8.88, S 16.26. Negative 

 FeCl,, ninhydrin, Fehling. 



