6ii Unclassified Metabolites 



M. H. McCormick, W. M. Stark, G. E. Pittenger, R. C. Pit- 

 tenger and J. M. McGuire, "Antibiotics Annual 1955-1956," 

 Medical Encyclopedia, Inc., New York, p. 606. 



H. Nishimura, Ann. Kept. Shionogi Res. Lab. 1 479 (1957). 



1301 Variotin, Ci.sH^jyOiN, colorless oil, [a],r' -5.68° (c 1.0 in meth- 



anol). 



A neutral oil with an ester-like odor. C 67.35, H 8.58, 

 N 4.16, contains no halogen, sulfur or phosphorus. Posi- 

 tive diazo, nitroalkyl and hydroxamic acid reactions; nega- 

 tive ferric chloride, Millon, Ehrlich, Sakaguchi, Molisch, 

 biuret, xanthoprotein and ninhydrin tests. 



Paecilomyces variotis Bainier var. antibioticus 

 Hiroshi Yonehara, Setsuo Takeuchi, Hakao Umezawa and 

 Yusuke Sumiki, /. Antibiotics (Japan) 12A 109, 195 (1959). 



1302 Vengicide, C04H09O9N10, white, amorphous, m.p. 241.5-243°, 



[a]i>-" —51.6° (in 0.1 N hydrochloric acid solution). 



Mol. Wt. -600. U.V. Amax. 233.5 and 273.5 m^x in 0.05 

 N hydrochloric acid. C 47.05, H 4.85, O 24.85, N 23.85. 



Streptomyces vendargensis 



Oxytetracycline is produced also in this fermentation. 



N. V. Koninklijke Nederlandsche Gist — en Spiritus — fabriek, 

 British Patent 764,198 (1956). (Chem. Abstr. 51 10009a) 



A. P. Struyck, Canadian Patent 514,164 (1955). 



1303 Vertimycin C, crystalline, m.p. 152-155°. C 62.4, H 6.84, O 



21.9, N 8.0. 



Streptomyces verticillatus 

 Canadian Patent 575,235 (1959). 



1304 Violacetin, fine yellow needles, m.p. (hydrochloride) >210°. 



Basic compound. Positive ninhydrin, diazo tests. Pre- 

 cipitated from aqueous solution by picric acid, phospho- 

 tungstic acid, forms reineckate. Analysis: C 38.26, H 

 6.74, N 24.71, CI 9.33. Negative biuret, Fehling, ninhy- 

 drin, glucosamine, maltol, Sakaguchi, Millon, xanthopro- 

 tein. 



Streptomyces sp. resembling S. purpurochromogenes 

 Kazuyoshi Aiso, Tadashi Aral, Ichiro Shidara, Hiroo Kurihara 

 and Yoshiro Morita, /. Antibiotics (Japan) 8A 33 (1955). 



1305 Violarin, C22-24H.i:j .S4OS-9, dark violet color or amorphous red 



powder, dec. 130°, somewhat similar to litmocidin, rubidin 

 and rhodomycetin. 



