Pfizer Handbook of Microbial Metabolites 612 



Streptomyces violaceus 



N. A. Krasilnikov, G. K. Skryabin and O. I. Artamonova, 

 Antibiotiki (U.S.S.R.) 3 (1958). 



Idem., J. Antibiotics (Japan) 13A 1 (1960). 



D. M. Trakhtenberg, L. V. Cerenkova and A. S. Chochlov, 

 Symposium on Antibiotics, Prague (1959). 



Viridins, CigHjgOe (isomers). 



1306 a-Viridin, fine colorless needles, m.p. 208-217° (dec), [a]D^° 



-213.4° (in chloroform). 



1307 yS-Viridin, Fine colorless needles, m.p. 140° (dec), [ajn^" -50.7° 



(in chloroform). 



Both compounds show: negative Schiff, FeCly, iodo- 

 form. Red- violet color with phloroglucinol-hydrochloric 

 acid. Positive ketone derivative tests, Fehling, Tollens. 



Tricho derma viride 



P. W. Brian and J. C. McGowan, Nature 156 144 (1945). 



P. W. Brian, P. J. Curtis, H. G. Hemming and J. C. McGowan, 

 Ann. Appl. Biol. 33 190 (1946). 



E. B. Vischer, S. R. Rowland and H. Raudnitz, Nature 165 

 528 (1950). 



1308 Virtosin, C27H40O9N2, colorless needles, m.p. 142.5-143°, [aW^ 



+80° ± 0.5° (c 1 in acetone). 



Positive Fehling and Sakaguchi reactions; negative 

 ninhydrin and maltol tests. 



Streptomyces olivochromogenes 



Akira Miyake, Shozo Wada, Motoo Shibata, Koichi Naka- 

 sawa, Jujo Kaneko and Yasuharu Mamiya (to Takeda Pharma- 

 ceutical Industries Ltd.), Japanese Patent Appl. 6149 (1957). 



1309 Wortmannin, colorless needles, m.p. 240° (yellowing in sun- 



light). 



A neutral antifungal antibiotic, containing only C, H, O. 

 Yields were about 100 mg. per liter. 



Penicillium wortmanni Klocker 



P. W. Brian, P. J. Curtis, H. G. Hemming and G. L. F. Nor- 

 ris, Brit. Mycol. Soc. Trans. 40 365 (1957). 



1310 Xanthicin, C].3H]-,0-,N, yellowish silky crystals, m.p. 211-213° 



(dec), [cxW +319° (c 0.25 in acetone). 



U.V. maxima at 270 m^ (CH3OH). 260 m^, 325 nifx 

 (0.1 MKOH). Positive aldehyde, indole, FeClg tests. 

 Negative amino, nitro, Fehling's, phosphomolybdic acid 

 tests. Alkaline KMn04 oxidation gives succinic acid. 



