6i3 Unclassified Metabolites 



Streptomyces xanthochromo genes 



Yasuji Sekizawa and Keiko Miwa, Nippon Noget-kagaku 

 Kaisld 30 471 (1956). 



1311 Xanthomycin-like Antibiotic, C29n420-N,)S4Cr (Reineckate), yel- 



low-orange glass, U.V. 264.5, 335 m^^ in water, pH 2. 



Positive Benedict, bromine, silver nitrate, potassium 

 iodide, sodium hydrosulfite and periodic acid. 



Streptomyces sp. 



James D. Mold and Quentin R. Bartz, /. Avi. Chem. Soc. 72 

 1847 (1950). 



1312 Xanthomycins (Protomycins), C23H09.31O7N3, free base: deep 



orange-red amorphous solid. Dihydrochloride : bright 

 orange-yellow plates, [a]ir^ -fll5° (c 0.4 in water). 

 Reineckate: long, orange needles, m.p. 165-170° (dec). 



Contains components A and B. Acid hydrolysis yields 

 ethanolamine, methylamine and ammonia. Red-purple 

 color with alkali. Positive Bro uptake, Benedict, silver 

 nitrate, sodium hydrosulfite, ketone derivatives. Negative 

 ninhydrin, Molisch, Sakaguchi, FeCls. 



Streptomyces sp. 



C. B. Thorne and W. H. Peterson, /. Biol. Chem. 176 413 

 (1948). 



K. V. Rao and W. H. Peterson, /. Am. Chem. Soc. 76 1335 

 (1954). 



1313 Xanthothricin, yellow needles, m.p. 165° (s. 161-162°). 



Analysis: C 43.64, H 3.82, N 35.21, O 17.34. 



Streptomyces sp. similar to S. albus 



Roy A. Machlowitz, W. P. Fisher, Betsey S. McKay, Al- 

 fred A. Tytell and Jesse Charney, Antibiotics and Chemo- 

 therapy 4 259 (1954). 



