691 Addendum 



tion of the pyridine moiety adjacent to the carbonyl 

 group in the mikamycin. '-'•'" 



An antiviral polypeptide, ccphaloniycin, has been re- 

 ported.'"' It contained leucine, alanine, valine, arginine, 

 glutamic acid, aspartic acid, glycine, threonine, tyrosine, 

 phenylalanine and three unidentified ninhydrin-positive 

 substances. 



Some peptide sequences of colimycin have been deter- 

 mined.'" It resembles polymyxin B, and the sequence 

 L-Dia — L-Dia — D-Leu — L-Leu — L-Dia — L-Dia — L-Dia — l- 

 Dia — L-Thr has been established (L-Dia = a, y-L-diamino- 

 butyric acid). 



An antibiotic named colisan has been isolated from a 

 bacillus.'^- '-'' 



Sporidesmolide I, a metabolic product of Sporidesmium 

 bakeri Syd., colorless needles, m.p. 261-263°, [a],,'" 

 —217° in chloroform (c 1.5) has the empirical formula 

 C33H58OSN4 and the structure : "^^ 



CH3 CH3 



\ / 



CH 



\^° 



CH3 



/ \ 



C' CHj 



CH; 



-CH 



\ 

 CH. 



\ 

 CH 



/ \ 

 CH3 CH3 



129a xiyoshe Watanabe, Hiroshi Yonehara, Hamao Umezawa and 

 Yusuke Sumiki, /. Antibiotics (Japan) 13A 293 (1960). 



""Akihiro Matsumae, /. Antibiotics (Japan) 13A 143 (1960). 



"^ Michel Dautrevaux and Gerard Biserte, Compt. rend. soc. biol. 

 153 1346 (1959). 



132 R. Reitler and J. Boxer, Nature 158 26 (1946). 



133 R. Reitler and A. Berner, to be published. 



"3" D. W. Russell, Biochim. et Biophijs. Acta 45 411 (1960). 



