Pfizer Handbook of Microbial Metabolites 



700 



More data have been published on the purification and 

 physical properties of mycobacillin (entry 795).^'^ 



Some degradation studies of thiostreptone (entry 809) 

 have been reported/'* L-Threonine, L-isoleucine, l- 

 alanine and D-cysteine were identified, and several thia- 

 zole-containing fragments were isolated. A minimal 

 molecular weight of 1500 is required. 



A structure has been proposed for a new antibiotic, 

 racemomycin O.^"'^ It is produced by Streptomyces race- 

 mochromo genus, has the empirical formula C25H44O10N8 

 and is thought to be : 



HO CH. 



l/\ 

 CH2 CH— C 



I I I 



HN N C 



\/ X\ / 

 CO N 



I H 



NH 



NH 



\ 



HC 



HC— NH CO— CH2— CH— CH2— CH2— CH2— NH2 



I 

 HOCH O NH2 



I 

 HC— O 



I 

 HC CH— CH2— CH2— O— CH2— CH— CH3 



CH2— O 1 OH 



A partial structure has been advanced for roseothricin 

 A (entry 717).^"'' 



^" S. K. Majumdar and S. K. Bose, Arch. Biochem. and Biophys. 

 90 154 (1960). 



^'* Miklos Bodanszky, John Timothy Sheehan, Josef Fried, Nina J. 

 WiUiams and Carolyn A. Birkheimer, 7. Am. Chem. Soc. 82 4747 

 (1960). 



i"S. Takemura, Chem. & Pharm. Bull. (Tokyo) 8 578 (1960). 



1^8 T. Goto, Y. Hirata, S. Hosoya and N. Komatsu, Bull. Chem. 

 Soc. Japan 30 729 (1957). 



