Pfizer Handbook of Microbial Metabolites 710 



72. PURINES 



Guanosine diphosphate glucose and guanosine diphos- 

 phate fructose are produced by Eremotheciiim ashbyii.^^^ 

 A dissertation reports the isolation of a new guanine de- 

 rivative from a riboflavin producer.""" 



A new purine riboside has been isolated from fusarium 

 species.'-^ It has been assigned the provisional struc- 

 ture: 



2-( 1 -Carboxyethylamino )-6-hydroxy-9-D-ribofuranosyl- 

 purine 



OH 





CH;,— CH— HN 

 COOH 

 H:03P— O— CH, 



OH OH 



Nebularine (9-/?-D-ribofuranosylpurine), produced by 

 Agaricus nebularis, has been isolated from a strepto- 

 mycete.--^" 



The nucleotides of Aspergillus oryzae have been char- 

 acterized. --- 



The mechanism of action of the antibiotic, psicofura- 

 nine, against Staphylococcus aureus has been studied. ^'^ 

 A possible effect may be interference with the biosynthe- 

 sis of guanylic acid from xanthylic acid. 



219 H. G. Pontis, A. L. James and J. Baddiley, Biochem. J. 75 428 

 (1960). 



220Usama A. S. Al-Khahdi, Dissertation Abstr. 21 (1960). 



"1 Alessandro Ballio, Carlo Delfini and Serena Russi, Nature 186 

 968 (1960). 



'"'" Kiyoshi Osono and Saburo Suzuki, /. Antibiotics (Japan) ISA 

 270 (1960). 



*'-- Kazuo Okunuki, Kozo Iwasa, Fumio Imamoto and Tadayoshi 

 Higashiyama, /. Biochem. (Tokyo) 45 795 (1958). 



"•''Ladislav J. Hanka, J. Bacterial. 80 30 (1960). 



