HISTOLOGY 



99 

 The 



nuclei, surrounded by small amounts of non-granular cytoplasm 

 nucleus contains one or two intensely staining nucleoli. 



There are two kinds of chromophil cells. Stained with hematoxylin and 

 eosin, the cytoplasmic granules of some cells take the hematoxylin stain — 

 these are the basophil cells; others take the eosin stain — these are the 



-• • 





^ ' *• 





-Pars nervosa 



Pars intermedia 



Residual lumen 



Pars distalis 



Fig. 41. — Hypophysis. Fixed in io',~c formalin. (X^oo.) 



acidophil cells. The basophils are large polyhedral cells with eccentric 

 nuclei and a large amount of cytoplasm. Variations exist in the amount and 

 size of the basophilic granules. The cytoplasm often contains vacuoles of 

 different size. 



The acidophils are small, round or oval cells with centrally located nuclei. 

 The nucleus contains a large acidophilic and a smaller basophilic nucleolus. 



\'ariations exist in the relative number of the three types of cells. The 

 number of degranulated basophil cells increases during pregnancy (61). 

 After castration the basophil cells increase in number and in size, and in some 

 of them cytoplasmic vacuoles are present (castration cells). 



