222 



BIOLOGY OF THE LABORATORY MOUSE 



these papillomas showed beginning adenocarcinoma (Fig. 121B). Primary 

 fibrosarcoma also occurs in this organ. Slye (57) reported on kidney tumors 

 of several types. 



Although tumors of the urinary bladder are extremely rare, papillomas 

 have been found. One extensively invading and rapidly growing carcinoma 



P^iG. 121. — Tumors of the renal pelvis. A, papilloma of the renal pelvis (X200); 

 B, adenocarcinoma in a papilloma of the renal pelvis (X200). 



of the transitional cell epithelium occurred in a Riga stock female. Hem- 

 angiomas are also seen (Fig. iiiA). 



Ovarian Tumors 



Among the first reports on tumors of the ovaries in mice were those of 

 Jobling (30), Tyzzer (67) and Haaland (23). Slye, Holmes and Wells (56) 

 stated that they had found 44 primary ovarian tumors in 22,000 autopsies. 

 Gardner, Strong and Smith (19) described a case of spontaneous bilateral 

 granulosa cell tumors in an old mouse. J. Furth and Butterworth discuss 



