496 



INDEX 



Transplantation of tumors, arising in hybrids, 

 286 

 biological factors, role in, 299 

 chemical basis of, 288 

 diet, role in, 297 

 endocrine influence on, 314 

 factors influencing, 297 

 genetics of, 297 

 irritating agents, role in, 298 

 leukemia, 290 

 methods, 292 



number of genes involved, 283, 287 

 relation to individuality, 301 

 sex, role in, 299 

 useful sites, 293 

 value in growth studies, 297 

 Transplanted tumors, immunization against, 

 291 

 list of available, 294 

 mutations in, 288 

 physiological individuality of, 302 

 relation of to spontaneous, 301 

 storage in dry ice, 297 

 Trematoda, 359 

 Trichina spiralis, 369 

 Tricliinella spiralis, 369 

 Trichinosis, 369 

 Trichomonas miiris, 351 

 Trichophyton ectothrix »ic gal os pari u>n, 430 

 Trichophyton gypseum, 430 

 Trichophytosis, 430 

 Trophectoderm, 7 



as origin of giant cells, 40 

 relation to decidua, ^^ 

 Trypanosoma duttoni, 353 



control measures, 358 

 Icu'isi, 353 

 Tumor incidence, affected by .1" gene, 260 

 by ova transfer, 258 

 difference in reciprocal hybrids, 251 

 endocrine influence on, 259, 310 

 estrous cycle and, 312 

 extra-chromosomal influence in, 251, 



262, 266, 273 

 frequency of breeding and, 312 

 in backcross generations, 256 

 in castrate mice, 311 

 influence of milk on, 257, 321 

 lower in virgin females, 259, 311 

 nematode infection and, 369 

 tapeworm infection and, 360 



Tumor incidence, tissue transplants increase, 



Tumors, benign, 171 



characteristics of, 169 



classification of, 171, 175, 214, 223 



definition of, 169 



etiology, 171 



formation (see tumor incidence) 



hormones produced by, 315 



immunization to transplanted, 291 



in A strain (see A strain) 



in C57 black (see C57 black) 



in dba strain (see dba strain) 



in Y strain, 269 



inheritance of mammary, 259 



linkage not found, 264 



lymphatics in, 170 



malignancy in mice, 168 



malignant, 171 



mammary (see mammary tumors) 



metastasis of, 170 



of primary lung, 211 

 morphological symptoms, 170 

 multiple, 168 

 nerves in, 170 

 non-epithelial, 268, 269 

 of blood forming organs, 212 

 of body wall, 199 

 of central nervous system, 228 

 of dermis, 199 

 of digestive system, 219 

 of epidermis, 195 

 of gall bladder, 219 

 of histiocytes, 217 

 of kidney, 221 

 of liver, 219 



of lung, 208, 212 (see also lung) 

 of lymphocytes, 2 1 5 

 of mammary region, 174 

 of monocytes, 217 

 of myeloid cells, 216 

 of ovary (see ovarian tumors) 

 of pancreas, 221 

 of skin, 195 



of subcutaneous tissues, 195, 199 

 of submaxillary gland, 219 

 of testis, 227 

 of urinary bladder, 221 

 of uro-genital system, 221 

 of uterus, 225 

 physiological individuality of, 302 



