664 



INDEX 



heat and, 528 

 measurement of, 526-527 

 deproteinization, 

 chloroform, 323-324 

 sodium chloride, 325-326 

 dichroism, 

 humidity and, 539--541 

 infrared, 550 

 stained, 544-545 

 digests, 

 intestinal phosphatase and, 589 

 phosphodiesterase and, 586 

 dimensions of, 489-490 

 diversity of, 351-358 

 enzyme combination with, 321 

 fractionation, 

 general, 358-361 

 of protein nucleates, 361-366 

 theories regarding, 365-366 

 GC type, 350 



hydrogen-bonding in, 480, 489, 490 

 hydrogen-ion concentration and, 490- 



492 

 hydrolysis of, 196-197 

 formic acid, 259 

 hydrochloric acid, 258 

 perchloric acid, 258 

 products, 191-192 

 hyperchromic effect, 339 

 infrared absorption of, 548-549, 553 

 integrity, 321-322 



standards of, 333-337 

 inter-nucleotide distance, 461 

 intestinal phosphatase and, 589 

 isolation of, 321-333 



anionic detergents, 327-328 

 comparison of procedures, 328-329 

 microorganisms, 330-332 

 miscellaneous, 329-330 

 removal of impurities, 332-333 

 strong salt solution, 323-326 

 water, 326-327 

 light scattering and, 484, 487, 489, 490, 



491-492 

 localization of, 6 



mammalian, composition of, 352-355 

 microbial, composition of, 356-358 

 models, 

 Astbury, 461-462, 539 

 Furberg, 462, 464 

 Pauling and Corey, 463-464 



Watson and Crick, 371, 464-470, 480, 

 541,548 

 moisture content, 334, 552 

 molecular weight determination, 337 

 dielectric dispersion, 473 

 diffusion coefficient, 471-472 

 light-scattering, 472^73 

 ultracentrifugation, 470-471 

 nucleotide sequence, 366 

 optical activity, 336-337 

 paracrystalline form of, 468, 552 

 phosphate groups, position of, 463 

 phosphodiesterase and, 587 

 protein combination of, 311-312, 320- 



321 

 purity, criteria of, 322-323 

 sedimentation of, 491 

 solution properties, 

 ionic strength, 483-488 

 pH effects, 490^92 

 size and shape, 488-490 

 stabilization, cations and, 527-528 

 structure, 366-368 

 helical, 463-464, 468^70 

 pattern, 461-462 

 similarities, 369-371 

 titration, 490 



anomalies, 476^77, 522-525 

 transforming activity, 328, 331 

 ultraviolet absorption, 



deoxyribonuclease and, 519 

 electrolytes and, 488 

 viscosity, 489-492 

 pH and, 479^80 

 x-ray diffraction of, 461, 467, 469-470, 



552 

 yeast, purification of, 325 

 Deoxypentose nucleoprotein, 

 infrared absorption of, 553 

 D-2-Deoxyribofuranosides, 138 

 2-Deoxyribonic acid, formation of, 59-60 

 Deoxyribonuclease, 162, 233, 277, 321, 

 367, 441, 552 

 action, 

 products of, 345, 442 

 volume changes and, 564 

 antibodies against, 625 

 assay, 



acid group formation, 579 

 acid-soluble phosphorus and, 579-580 

 dye-binding and, 580-581 



