INDEX 



673 



I 



Imidazole, dissociation constant, 456, 458 

 6-Iminodih3'dropyrimidine, 448 

 Indole-hj'drochloric acid reaction, 



comparative value of, 300 



deoxypentose nucleic acid, 

 mechanism of, 298 

 procedures, 297-298 

 specificity of, 297, 298 

 Infrared absorption, 



dichroism and, 550-551 



mulled samples, 546 



nucleic acids and, 545-551 



solvents and, 546 



sublimed samples, 546 

 Inosine, 36, 157, 165, 594 



adenine deamination and, 600 



dissociation constants of, 459 



formation, 



adenine and, 602-603 

 adenosine and, 142 



glycosidic linkage of, 143 



hydrolysis of, 606 



phosphorolysis of, 602, 603, 604 



thymidine phosphorylase and, 605 



uridine hydrolase and, 606 

 Inosine diphosphate, transphosphoryla- 



tion of, 626 

 Inosine-5'-phosphate, see also Inosinic 

 acid 



structure of, 162-163 



ultraviolet absorption of, 505, 508, 510 



synthesis of, 173 



ultraviolet absorption of, 512 

 Inosine triphosphate, 



ami nation of, 600 



ultraviolet absorption of, 512 

 Inosinic acid, 39, 40, 597, see also Inosine 

 phosphate 



biosynthesis of, 607 



conversion to hypoxanthine, 197 



conversion to inosine, 197 



isomers, ion-exchange of, 228 



origin of, 160 

 Inosinic acid transformj'lase, 



assay of, 614 



cofactors of, 614 



purine synthesis and, 614 

 Iodine, reaction with pyrimidines and 

 purines, 121 



lodoacetamide, deoxyribonuclease and, 



582 

 lodoacetic acid, deoxyribonuclease and, 



582 

 5-Iodouracil, 370 

 incorporation of, 347 

 thymidine phosphorylase and, 605 

 Ion-exchange, 

 anionic, nucleic acid derivatives and, 



219-220 

 cationic, nucleic acid derivatives and, 



218-219 

 equilibria, 

 distribution coefficient, 213-214 

 hj'drophilic character, 213 

 non-polar affinity, 214 

 rate of reaction, 214-215 

 Iron, 

 deoxyribonuclease and, 581 

 uricase and, 619 

 Isoamyl alcohol, paper chromatography 



and, 256-257 

 Isobarbituric acid, 83 

 barbiturase and, 623 

 formation from uracil, 120-121 

 uracil oxidase and, 622 

 Isobutyric acid, paper chromatography 



and, 253, 257 

 Isocytosine, 

 color tests for, 123 

 dissociation constants of, 456, 457 

 polarography and, 120 

 synthesis of, 125 

 reducing agents and, 120 

 Isodialuric acid, 123 



formation from uracil, 120-121 

 Isoguanine, 



conversion to xanthine, 117 

 2,8-dihydroxyadenine and, 595 

 formation from uric acid, 96 

 nitrous acid and, 118 

 occurrence of, 97 

 reducing agents and, 120 

 synthesis of, 133, 135 

 ultraviolet light and, 123 

 Isoguanosine, see also Crotonoside 

 isolation of, 13 



nucleoside phosphorylase and, 602 

 Isoleucine, diphenylamine and, 289-290 

 Isonicotinic acid hj'drazide, diphospho- 

 pyridine nucleotide and, 609 



