INDEX 



677 



5-Nitro-2,6-dichloropyrimidine, amina- 



tion of, 127 

 Nitrogen, 



content of pentose nucleic acid, 393-394 

 deoxypentose nucleic acid and, 334 

 Nitrogen mustards, deoxyribonuclease 



and, 582 

 Nitromalonaldehj'de, 125 

 bts-p-Nitrophenyl phosphate, phospho- 

 diesterase assay and, 585-586 

 5-Nitropyrimidines, purine synthesis 



and, 131 

 Nitrosocyanoacetate, purine synthesis 



and, 132 

 5-Nitrouracil, 104 



conversion to chloro derivative, 127 

 5-Nitrouridine, 143 

 Nitrous acid, effect on purines and 



pjrimidines, 118-119 

 Nucleases, 331, 332 

 definition, 557 



nucleoprotein isolation and, 313 

 spleen, specificity of, 432 

 Nuclei, 

 deoxyribonuclease and, 624, 625 

 enzymes in, 625 

 nucleic acid, analysis of, 209 

 pentose nucleic acid of, 400-402, 406 

 ribonuclease and, 624-625 

 Nucleic acids, 

 cellular, 



dichroism and, 542-544 

 infrared absorption and, 549 

 denaturation, ultraviolet absorption 



and, 514-516 

 derivatives, estimation of, 260-263 

 early history, 1-3 

 estimation, 



phosphorus and, 285-286 

 spectrophotometric, 529-530 

 hydrolysis of, 19-20 

 infrared absorption spectra of, 545-551 

 metabolism, 556-558 



enzymes of, 623-625 

 molar absorptivities of, 516-518 

 protein combinations, 530-532 

 ribose isolation from, 19-20 

 separation of, 192 

 structure, 

 infrared absorption and, 546 

 x-ray diffraction and, 461-470 



ultraviolet absorption, tetranucleotide 



theory and, 514 

 ultraviolet dichroism of, 532, 538-542 

 definition and equations, 535-537 

 form dichroism, 534-535 

 general theory of, 533-534 

 simple compounds, 537-538 

 stained nucleic acid, 544-545 

 Xucleohistone, 

 extinction of, 314 

 fractionation of, 361-366 

 isolation of, 310, 312-317 

 occurrence of, 311 

 phosphatase and, 577 

 solubility of, 314 

 Nucleoprotamines, 

 isolation of, 310, 312-317 

 occurrence of, 311-312 

 Nucleoproteins, 

 artifacts, 319-321 

 bacterial, isolation of, 314-315 

 cleavage of, 319 

 cysteine-sulfuric acid reaction and, 



295-296 

 dichroism, 541-542 



infrared, 551 

 diphenylamine and, 290 

 nature of, 311-312 

 nucleic acid content of, 318 

 properties, 317-321 

 purification of, 315 

 separation of, 317-318 

 spectrophotometric titration anomalies 



of, 531 

 ultraviolet absorption of, 318, 530-532 

 x-ray diffraction of, 531 

 /5-Nucleoprotein, 3 

 Nucleosidases, terminology, 600 

 Nucleoside diphosphates, 

 diesterase and, 422-423 

 electrophoresis, 282 

 Nucleoside-5'-phosphates, production of, 



161 

 Nucleoside phosphorylase, 



intracellular localization of, 625 

 riboside synthesis and, 36-37 

 Nucleoside polyphosphates, formation 



of, 625-626 

 Nucleosides, 

 borate complexes, 



