680 



INDEX 



criteria of, 384-385 



ribonuclease and, 407 

 dichroism and, 538 

 distribution of, 4-6 

 dye-binding and, 482-483 

 homogeneity, 392 



preservation of, 384-386 

 hydrolysis, 259-260 



acid, 192-196 



alkaline, 197-199, 483 



products, 191-192 

 infrared absorption of, 549, 553 

 intestinal phosphatase and, 589 

 isolation, 



animal tissues, 387-389 



general, 384-386 



microbial, 390-391 



plant tissues, 389-390 

 liberation of acid groups from, 199 

 metachromasy and, 545 

 molecular weight determination, 386, 



474-475 

 nature of, 391-394 

 nucleotide composition, 



analytical procedures, 395-396 



animal, 396-402 



general considerations, 394-395 



microbial, 402-403 



plant, 403-405 

 organ-specificity of, 406 

 phosphodiesterase and, 586, 587 

 polymerization of, 393 

 position in nucleotropomyosin, 382 

 purified, analysis of, 204-205 

 reaction with albumin, 381 

 reaction with cytoplasm, 381 

 regularity, inter specific, 406-407 

 removal from deoxypentose nucleic 



acid, 332-333 

 removal from tissues, 329 

 ribonuclease kinetics and, 570-572 

 species-specificity of, 405-406 

 titratable groups of, 481-482 

 ultracentrifugation of, 391 

 ultraviolet absorption, 393 



digests, 569-570 



ribonuclease and, 518-519 

 virus, function of, 405 

 Pentose nucleoprotein, 

 centrifugation of, 380-381 

 components, separation of, 380-382 



isolation, 



animal, 375-376 



general considerations, 374-375 

 microbial, 379 

 plant, 376-379 

 procedures, 376, 377, 378 

 nature of bonds, 379-383 

 Pentose phosphate isomerase, ribose-5- 



phosphate preparation and, 63 

 Pentoses, 

 cysteine-sulfuric acid reaction and, 



294-295 

 indole-hydrochloric acid reaction and, 

 297, 298 

 Pepsin, ribonuclease and, 574-575 

 Peptides, infrared dichroism and, 550 

 Perchloric acid, nucleic acid hydrolysis 



by, 195, 197 

 Periodate, 

 reaction of nucleosides, 147, 148-149 

 ribonuclease digests and, 424-425 

 ribonucleic acid end-group analysis 

 and, 438 

 Permanganate, pyrimidines and, 120 

 Phenobarbital, 103 

 Phenol, 

 paper chromatography and, 250, 257 

 xanthine oxidase and, 613 

 N-Phenyl-2-deoxyribosylamines, 56 

 o-Phenylene diamine, 21 

 Phenylhydrazine, reaction with uridine, 



144 

 Phloroglucinol, reaction with ribonucleic 

 acid, 

 procedure, 302 

 specificity, 302 

 Phosgene, purine synthesis and, 135 

 Phosphatase, 167, 199 

 action on nucleotides, 164 

 bone, nature of, 589-590 

 deoxyribonucleic acid and, 441 

 deoxyribonucleic acid digests and, 



576-577 

 liver, phosphate transfer by, 594 

 low specificity, 590 

 malt, phosphate transfer by, 594 

 nucleic acid hydrolysis and, 198 

 prostatic, 

 end-group analysis and, 437 

 nucleotides and, 590 

 phosphate transfer and, 594 



