684 



INDEX 



sublimed, ultraviolet absorption of, 

 501-504 



substituted, stability to alkali, 118 



synthesis of, 125-130 



transamination and, 599-600 



ultraviolet absorption of, 450-451 

 2,6-Pyrimidinethiols, sj^nthesis of, 127 

 Pyrimidones, 450 



Pyrogallol, xanthine oxidase and, 613 

 Pyronine-methyl green, 



dichroism and, 544 



specificity of, 544 

 Pyrophosphatase, 186 

 l-Pyrophosphoryl-5-phosphoryl ribose, 



nucleotide synthesis and, 607 

 Pyruvic acid, formation from thymine, 



121, 123 

 Pyruvic aldehyde, 



cysteine-sulfuric acid reaction and, 295 



glyceraldehyde-3-phosphate and, 438 



Quinoline, paper chromatography and, 



253 

 Quinone imine, xanthine oxidase and, 



612-613 



Resins, 



cross-linkage, effect on nucleotide 

 separation, 233-234 



ion-exchange, properties of, 212-213 

 Resorcinol, hydroxyl bond length in, 449 

 Rhamnose, 



paper chromatographj' of, 264 



tryptophan-perchloric acid reaction 

 and, 296 

 D-Ribal, 17 



Ribazoles, see also 5,6-Dimethylben- 

 zimidazole riboside 



activity of, 31 



synthesis of, 61 



synthetic, activity of, 62 

 Ribazole phosphate, synthesis of, 61-62 

 Ribitol, 16, 48 



occurrence of, 15 

 Ribitol-5-phosphate, 163 

 1-Riboarsenate, nucleoside phosphoryl- 



ase and, 603 

 Ribobenzimidazole, 47, 141 



importance of, 31 

 preparation of, 21 

 Ribodesose, see Deoxyribose 

 Riboflavin, 15, 29 



Riboflavin phosphate, see also Flavin 

 mononucleotide 

 ion-exchange of, 232 

 synthesis of, 183 

 D-Ribofuranosyl adenine, nucleoside 



hydrolase and, 606 

 9-D -Ribofuranosyl -2,6-diaminopurine, 



synthesis of, 151 

 l-(Q:-D-Ribofuranosyl)-5,6-dimethylben- 



zimidazole, 13 

 D-Ribonic acid, 12, 21, 141 

 reactions of, 47 

 ribose synthesis and, 16 

 Ribonolactone, 16, 17 

 Ribonuclease I, see Ribonuclease, pan- 

 creas 

 Ribonuclease, 430 

 action, 

 chemistry of, 423-428 

 mechanism of, 431 

 products of, 161-162 

 volume changes and, 563 

 amino acids of, 574-575 

 antibodies against, 625 

 assay, 

 manometric, 568-569 

 phosphorus and, 566 

 spectrophotometric, 566-567 

 turbidimetric, 566 

 bacterial, 576 



cyclic phosphates and, 425-426 

 definition of, 557 

 digests, 



dialysis of, 423 

 electrophoresis of, 279-282 

 ion -exchange of, 234-235 

 nucleotide isomers in, 425 

 periodate and, 424 

 enolic group liberation by, 412 

 inhibition of, 385-386, 571 

 intracellular localization of, 624-625 

 isolation of, 572-573 

 molar absorptivities and, 518-519 

 mononucleotide esters and, 430 

 nucleic acid separation by, 332-333 

 oligonucleotides and, 426-427 



