INDEX 



685 



pancreas, 



assay of, 566-567, 568-569 



history, 558-559 



homogeneity of, 573 



hydrogen ion concentration and, 572 



hydrolytic products of action, 560- 

 563 



inhibitors, 572 



kinetics of, 570-572 



mechanism of action, 563-565 



nucleotide esters and, 565 



physicochemical properties of, 573- 

 575 



protein nature of, 572-575 



specificity of, 559-560 



synthetic reactions of, 565-566 



temperature and, 572 



titrable acidic groups and, 567-568, 

 569 



ultraviolet absorption and, 569-570 

 pentose nucleic acid composition and, 



398-399 

 pepsin and, 574-575 

 performic oxidation of, 575 

 5'-phosphates and, 422 

 plant, 576 



pyrimidine nucleotides and, 423-424 

 removal of, 387, 398 

 secondarj' phosphoryl and, 423 

 specificity of, 427-428 

 spleen, 



mechanism of action, 575-576 



specificity of, 575 

 test for pentose nucleic acid, 4, 6 

 transesterification and, 566 

 transphosphorylation and, 563 

 turnip yellow mosaic virus and, 382 

 Ribonucleic acid, 3, see also Pentose 



nucleic acid 

 adenine estimation in, 304 

 alkali lability of, 416 

 branching of, 422, 432-436 

 color reactions for, 



cysteine-sulfuric acid, 302-303 



evaluation of, 303 



orcinol, 300-302 



phloroglucinol, 302 

 contamination, removal of, 325 

 cores, 412 



depolymerization of, 431 

 diesterase and, 434-435 



electrometric titration of, 410 

 end-group analysis of, 437-438 

 hydrolysis, 429-430 



alkaline, 418-419 



cyclic intermediates, 419 



enzymatic, 421 

 indole-hydrochloric acid reaction and, 



297 

 internucleotidic linkages, 420-422 

 lability of, 478-479 

 methylation of, 433-434 

 monomers of, 438-439 

 phosphate linkages in, 422-423, 430-432 

 spleen nuclease and, 432 

 x-ray diffraction of, 461, 470 

 Ribonucleosides, 604 



stereochemistry of, 417-418 

 Ribonucleotides, 



acid-base properties of, 477-479 

 cation exchange behavior, 219 

 cyclic, electrophoresis of, 279-280 

 separation from other phosphorus com- 

 pounds, 277-279 

 D-Ribopyranosyl adenine, 



nucleoside hydrolase and, 606 

 synthesis of, 152-153 

 D-Ribose, 3, 10 

 acetals of, 46 



acj'lderivatives, purification of, 19 

 anhydrides of, 46-47 

 browning of, 14 



chromatography of, 21-22, 24, 263-264 

 compounds containing, 13 

 derivatives, 20-21 



occurrence of, 15 



properties of, 65-74, 79-80 

 dissociation constants and, 458 

 esters of, 43-46, 63-64 

 ethers of, 42-43 

 form in nucleic acid, 12 

 N -glycosides of, 27-33 

 0-glycosides of, 24-27 

 identification and estimation, 11-12, 



20-22, 140-141 

 ionic behavior of, 219 

 isotopic, 61 

 liberation from pentose nucleic acid, 



193 

 mutarotation of, 22-23 

 natural occurrence of, 60 

 pentose nucleic acids and, 394 



